- Search results for 215543-92-3
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3 products were found matching "215543-92-3"!
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Item number: Cay13182-5
SU 5402 is an inhibitor of the tyrosine kinase domains of VEGFR2, FGFR1, and PDGFRbeta (IC50s = 0.02, 0.03, and 0.51 µM, respectively). It is much less effective against other receptor tyrosine kinases. SU 5402 is commonly used to evaluate the role of FGFR1 in cellular functions.Formal Name:...
| Keywords: | 2-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-1H-pyrrole-3-propanoic acid |
| Application: | FGFR1 /?VEGFR2 inhibitor |
| CAS | 215543-92-3 |
| MW: | 296.3 D |
From 42.00€
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Item number: TGM-T6996-25mg
Description: SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 values of 20 nM for VEGFR2, 30 nM for FGFR1, and 510 nM for PDGF-Rbeta. Target: PDGFR, VEGFR, FGFR. Smiles: C(=C1C=2C(NC1=O)=CC=CC2)C3=C(CCC(O)=O)C(C)=CN3. References: Sun L, et al. J Med Chem. 1999, 42(25), 5120-5130.
| Keywords: | SU5402 |
| Application: | FGFR1 /?VEGFR2 inhibitor |
| CAS | 215543-92-3 |
| MW: | 296.32 D |
From 56.00€
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Item number: LKT-S801001.25
Inhibitor of VEGFR and FGFR.
| Keywords: | SU5402, 3-[3-(2-Carboxyethyl)-4-methylpyrrol-2-methylidenyl]-2-indolinone |
| Application: | FGFR1 /?VEGFR2 inhibitor |
| CAS | 215543-92-3 |
| MW: | 296.33 D |
From 141.00€
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