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Item number: Cay29493-1

BMS 753 is a synthetic retinoid and retinoic acid receptor alpha (RARalpha) agonist (Ki = 2 nM). It is selective for RARalpha over RARgamma at 1 µM. BMS 753 (10 and 100 nM) induces morphological differentiation of P19 embryonal carcinoma cells, as well as F9 embryonal carcinoma cells when used at a concentration of...

Keywords:	4-[[(2,3-dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]-benzoic acid
Application:	Synthetic retinoid, RARalpha agonist
CAS	215307-86-1
MW:	351.4 D

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BMS 753

Item number: TGM-T22049-100mg

Description: BMS 753 is an agonist of isotype-selective retinoic acid receptor alpha (RARalpha, Ki= 2 nM). Target: Retinoid Receptor. Smiles: CC1(C)C(=O)C(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O. References: M Géhin, et al. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and...

CAS	215307-86-1
MW:	351.4 D

From 55.00€ *

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Review

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