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Item number: Cay28926-1

AZD 5991 is an inhibitor of myeloid cell leukemia-1 (Mcl-1, IC50 = 0.72 nM). It is selective for Mcl-1 over Bcl-2, Bcl-xL, Bcl-W, and Bfl-1 (IC50s = 20, 36, 49, and 24 µM, respectively). AZD 5991 decreases the viability of MV4-11 acute myeloid leukemia (AML) and MOLP-8 multiple myeloma (MM) cells with EC50 values of...

Keywords:	(3aR)-5-chloro-2,11,12,24,27,29-hexahydro-2,3,24,33-tetramethyl-22H-9,4,8-(metheniminomethyno)-14,20:26,23-dimetheno-10H,2...
Application:	Mcl-1 inhibitor
CAS	2143061-81-6
MW:	672.3 D

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