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Item number: Cay21870-25

Picrotin is a natural picrotoxane that antagonizes glycine receptors (GlyRs, IC50s = 57 and 117 µM for alpha1 and alpha2 homodimeric GlyRs, respectively). It also inhibits alpha3 homodimeric GlyRs. Picrotin is inactive in inhibiting gamma-aminobutyric acid (GABA) type A and type C receptors. Picrotin occurs in the...

Keywords:	(1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-3,6-methano-8H-1,5,7-trioxacyclo...
Application:	GlyR antagonist
CAS	21416-53-5
MW:	310.3 D

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