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Picrotin
Item number: Cay21870-25
Picrotin is a natural picrotoxane that antagonizes glycine receptors (GlyRs, IC50s = 57 and 117 µM for alpha1 and alpha2 homodimeric GlyRs, respectively). It also inhibits alpha3 homodimeric GlyRs. Picrotin is inactive in inhibiting gamma-aminobutyric acid (GABA) type A and type C receptors. Picrotin occurs in the...
| Keywords: | (1aR,2aR,3S,6R,6aS,8aS,8bR,9S)-hexahydro-2a-hydroxy-9-(1-hydroxy-1-methylethyl)-8b-methyl-3,6-methano-8H-1,5,7-trioxacyclo... |
| Application: | GlyR antagonist |
| CAS | 21416-53-5 |
| MW: | 310.3 D |
From 51.00€
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Picrotin
Item number: TGM-T16533-100mg
Description: Picrotin is an inhibitor of glycine receptors. Picrotin blocks alpha2 GlyR, alpha1 GlyR, and alpha3 GlyR and can be used in studies about neurotransmission. Target: Chloride channel. Smiles: [H][C@@]12OC(=O)[C@@]([H])([C@]1([H])C(C)(C)O)[C@]1(O)C[C@H]3O[C@]33C(=O)O[C@@]2([H])[C@]13C. References: Li P,...
| Application: | GlyR antagonist |
| CAS | 21416-53-5 |
| MW: | 310.3 D |
From 30.00€
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