Description: 5,7-DIMETHOXYF LAVONE possessed remarkable leishmanicidal potential. Target: Anti-infection, P450. Smiles: COc1cc(OC)c2c(c1)oc(cc2=O)-c1ccccc1. References: Tasdemir D . Antitrypanosomal and antileishmanial activites of flavoids and their analogues : In vitro, in vivo, structure-activity relationship,...

5,7-Dimethoxyflavone (5,7-DMF) is a flavonoid that has been found in B. pandurata and has diverse biological activities. It induces the production of reactive oxygen species (ROS), cell cycle arrest at the G1 phase, and apoptosis in HepG2 liver cancer cells when used at concentrations of 10, 25, and 50 µM. In vivo,...