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ABBV-744
Item number: TGM-T4697-100mg
Description: ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS. Target: Epigenetic Reader Domain, HIV Protease. Smiles: CCNC(=O)c1cc2c(cn(C)c(=O)c2[nH]1)-c1cc(ccc1Oc1c(C)cc(F)cc1C)C(C)(C)O. References: Emily J....
| Keywords: | ABBV744 |
| Application: | BD2 bromodomain inhibitor |
| CAS | 2138861-99-9 |
| MW: | 491.55 D |
From 40.00€
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ABBV-744
Item number: Cay30470-10
ABBV-744 is an inhibitor of the bromodomain and extra-terminal domain (BET) family protein bromodomain 2 (BD2, Kis = 4.6, 4.9, 1.6, and 1 nM for BRD2, -3, -4, and -T, respectively). It is selective for BD2 over BD1 bromodomains in a time-resolved FRET (TR-FRET) assay (Kis = 1,162, 3,140, 521, and 917 nM for BRD2,...
| Keywords: | N-ethyl-4-[2-(4-fluoro-2,6-dimethylphenoxy)-5-(1-hydroxy-1-methylethyl)phenyl]-6,7-dihydro-6-methyl-7-oxo-1H-pyrrolo[2,3-c... |
| Application: | BD2 bromodomain inhibitor |
| CAS | 2138861-99-9 |
| MW: | 491.6 D |
From 94.00€
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