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Item number: Cay35488-10

Belotecan is an inhibitor of DNA topoisomerase I (IC50 = 0.119 µg/ml) and a derivative of the DNA topoisomerase I inhibitor camptothecin (Cay-11694). It inhibits the proliferation of various cancer cell lines, including KATO III stomach, HT-29 colon, A549 lung, MDA-MB-231 breast, and SKOV3 ovarian cancer cells...

Keywords:	(S)-CKD602, 7-[2-(N-isopropylamino)ethyl]-(20S)-Camptothecin, CKD602,...
Application:	DNA topoisomerase I inhibitor
CAS	213819-48-8
MW:	470 D

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Belotecan hydrochloride

Item number: TGM-T7551-100mg

Description: Belotecan hydrochloride (CKD-602) is a synthetic water-soluble camptothecin derivative and topoisomerase I inhibitor with potential antitumor activity. Target: Topoisomerase. Smiles: Cl.CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccccc4c(CCNC(C)C)c3Cn1c2=O. References: Kim Y M , Lee S W , Kim D Y , et al. The...

Keywords:	CKD-602
Application:	Targets DNA topoisomerase I [EC:5.6.2.1] (TOP1)
CAS	213819-48-8
MW:	469.96 D

From 30.00€ *

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