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JNJ-A07
JNJ-A07

Item number: Cay43714-1

JNJ-A07 is an inhibitor of the protein-protein interaction between dengue virus non-structural protein 3 (NS3) and NS4B (EC50 = 35 nM in a pull-down assay). It inhibits replication of 21 dengue virus clinical isolates in Vero E6 cells (EC50s = 0.07-0.3 nM). JNJ-A07 reduces dengue virus RNA levels in mosquitos (A....
Keywords: (+)-4-[3-[[1-(4-chlorophenyl)-2-[2,3-dihydro-6-(trifluoromethoxy)-1H-indol-1-yl]-2-oxoethyl]amino]-5-methoxyphenoxy]-butan...
Application: Dengue virus NS3-NS4B protein-protein interaction inhibitor
CAS 2135640-93-4
MW: 578.97 D
From 137.00€ *
Review
(+)-JNJ-A07
(+)-JNJ-A07

Item number: TGM-T64092-100mg

Description: (+)-JNJ-A07 is a pan-serotypic dengue virus inhibitor that targets NS3-NS4B interaction with high potency. (+)-JNJ-A07 has antiviral activity and can be used to study dengue virus infections. Target: Virus Protease, Anti-infection. Smiles:...
CAS 2135640-93-4
MW: 578.96 D
From 62.00€ *
Review