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R-IMPP
Item number: TGM-T4058-100mg
Description: R-IMPP is an inhibitor of PCSK9 translation. R-IMPP stimulates uptake of LDL-C in hepatoma cells by increasing LDL-R levels, without altering levels of secreted transferrin. Target: Others, Serine/threonin kinase. Smiles: COc1ccc(CCC(=O)N([C@@H]2CCCNC2)c2nccc3ccccc23)cc1. References: Petersen DN., et...
| Application: | Cell-permeable PCSK9 inhibitor |
| CAS | 2133832-83-2 |
| MW: | 389.49 D |
From 42.00€
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(R)-IMPP
Item number: Cay20861-1
(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9, IC50 = 4.8 µM). It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels. (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of...
| Keywords: | (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide |
| Application: | Cell-permeable PCSK9 inhibitor |
| CAS | 2133832-83-2 |
| MW: | 389.5 D |
From 77.00€
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