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YW2065

Item number: Cay42959-10

YW2065 is an inhibitor of Wnt/beta-catenin signaling and an activator of AMP-activated protein kinase (AMPK). It induces degradation of beta-catenin and increases the levels of Axin1 and phosphorylated AMPK and acetyl-CoA carboxylase (ACC), which is a downstream substrate of AMPK, in SW620 colorectal cancer cells...

Keywords:	1-(2-bromophenyl)-5-methyl-N-2-quinolinyl-1H-pyrazole-4-carboxamide
Application:	Wnt/beta-catenin inhibitor, AMPK activator
CAS	2131223-85-1
MW:	407.27 D

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