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Item number: Cay45601-10

OPB-171775 is a molecular glue. It induces the formation of a complex between phosphodiesterase 3A (PDE3A) and ribonuclease SLFN12. OBI-171775 (10 nM) induces G0/G1 phase cell cycle arrest, apoptosis, and necrosis in PFSK-1 primitive neuroectodermal tumor cells, with cell cycle arrest partially blocked by the...

Keywords:	6-[2,3-difluoro-4-(2-hydroxy-2-methylpropoxy)phenyl]-4,5-dihydro-5-methyl-3(2H)-pyridazinone
Application:	Molecular glue
CAS	2131210-15-4
MW:	312.32 D

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