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GLPG2938
Item number: Cay34318-1
GLPG2938 is sphingosine-1-phosphate receptor 2 (S1P2) antagonist. It inhibits S1P-induced calcium flux in CHO cells overexpressing human S1P2 (IC50 = 8.8 nM). GLPG2938 inhibits S1P-induced IL-8 release in HFL1 cells (IC50 = 0.6 nM) and S1P-induced contraction of human lung fibroblasts. In vivo, GLPG2938 (3, 10, and...
| Keywords: | N-[2-ethoxy-6-(trifluoromethyl)-4-pyridinyl]-N'-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-3-pyridazinyl]... |
| Application: | S1P2 antagonist |
| CAS | 2130996-00-6 |
| MW: | 503.4 D |
From 93.00€
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GLPG2938
Item number: TGM-T9199-100mg
Description: GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent and selective antagonist of S1P2. Target: LPL Receptor, S1P Receptor. Smiles: CCOc1cc(NC(=O)NCc2cc(C)c(nn2)-c2cn(C)nc2C(F)(F)F)cc(n1)C(F)(F)F....
| Keywords: | 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)m... |
| Application: | S1P2 antagonist |
| CAS | 2130996-00-6 |
| MW: | 503.4 D |
From 72.00€
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