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TP0472993
Item number: TGM-T67916-100mg
Description: CYP4A11/CYP4F2-IN-2 is a potent and orally active dual inhibitor of cytochrome P450 (CYP) 4A11 and CYP4F2, with IC50 values of 140 nM and 40 nM, respectively. Extractable from liver and kidney, CYP4A11/CYP4F2-IN-2 has the potential to treat kidney diseases. Target: P450. Smiles:...
| Application: | CYP4A11 / CYP4F2 inhibitor |
| CAS | 2126874-77-7 |
| MW: | 300.36 D |
From 45.00€
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TP-0472993
Item number: Cay39757-10
TP-0472993 is an inhibitor of the cytochrome P450 (CYP) isoforms CYP4A11 and CYP4F2 (IC50s = 140 and 40 nM, respectively). It is selective for CYP4A11 and CYP4F2 over a panel of eight additional CYPs at 10 µM. TP-0472993 inhibits 20-HETE (Cay-90030) production in rat renal microsomes (IC50 = 347 nM). In vivo,...
| Keywords: | 1-[4-[[[6-(1H-pyrazol-3-yl)-3-pyridinyl]oxy]methyl]-1-piperidinyl]-ethanone |
| Application: | CYP4A11 / CYP4F2 inhibitor |
| CAS | 2126874-77-7 |
| MW: | 300.4 D |
From 140.00€
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