2 products were found matching "212631-61-3"!

No results were found for the filter!

PD 198306

Item number: Cay23966-1

PD 198306 is an orally bioavailable and potent inhibitor of MAPK kinase 1/2 (MEK1/2, IC50 = 8 nM). It is selective for MEK1/2 over ERK, c-Src, PI3Kgamma, and cyclin-dependent kinases (IC50s = >1 µM). PD 198306 (3-100 µM) reduces ERK1/2 phosphorylation and inhibits growth of HL-60 cells in vitro. In vivo, PD 198306...

Keywords:	N-(cyclopropylmethoxy)-3,4,5-trifluoro-2-[(4-iodo-2-methylphenyl)amino]-benzamide
Application:	MEK1/2 inhibitor
CAS	212631-61-3
MW:	476.2 D

From 100.00€ *

Show details

Review

PD 198306

Item number: TGM-T21980-100mg

Description: PD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1. Target: MEK. Smiles: N(C1=C(C(NOCC2CC2)=O)C=C(F)C(F)=C1F)C3=C(C)C=C(I)C=C3. References: Benoit Besson, et al. Kinome-Wide RNA...

CAS	212631-61-3
MW:	476.23 D

From 55.00€ *

Show details

Review

Didn't find the right Product? Here are some useful Search Tips!

Checklist-Thumbnail

All our products have English titles and descriptions. Therefore, use English search terms.
Write out Greek letters - i.e. "alpha" instead of α or "beta" instead of β.
Do not add "and" when entering multiple search terms.
Use the singular (e.g. "antibody" instead of "antibodies").
If available, try synonyms (e.g. for a specific protein).
You can search for chemical substances using the unique CAS number (Chemical Abstracts Service).
In addition, you can also use the UniProt or KEGG accession number for the product search.
Use our filter function to narrow down your search results. If you want to remove a selected filter again, click on the small "x" next to the filter.
Are you looking for products from a specific supplier? Then enter the corresponding supplier name and select it in the appearing suggestion field. Alternatively, you can also use our supplier overview.
Use - if known - the specific product number. Especially for short numbers, note the supplier code in front of each number for most of our partners (e.g. for AAT Bioquest "ABD-121" instead of just "121"). Click on the button below to find all supplier codes and additional information.

All Supplier Codes

We would be very happy to support you in your product search! Contact us at info@biomol.com.