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VU0810464
VU0810464

Item number: Cay43073-1

A GIRK1/2 and GIRK1/4 activator, induces GIRK1/2 and GIRK1/4 activity in a thallium flux assay using HEK293 cells expressing GIRK1 and GIRK2 or GIRK1 and GIRK4 (EC50s = 165 and 720 nM, respectively), reduces stress-induced hyperthermia at 10 and 30 mg/kg, i.p. in mice but does not affect the percentage of time spent...
Keywords: 3-chloro-N-(1-cyclohexyl-3-methyl-1H-pyrazol-5-yl)-4-fluoro-benzeneacetamide
Application: GIRK1/2 / GIRK1/4 activator
CAS 2126040-21-7
MW: 349.83 D
From 38.00€ *
Review
VU0810464
VU0810464

Item number: TGM-T7899-100mg

Description: VU0810464 is a non-ureaG protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. Target: Potassium Channel. Smiles: Cc1cc(NC(=O)Cc2ccc(F)c(Cl)c2)n(n1)C1CCCCC1. References: Discovery and Characterization of 1Hâ??Pyrazol-5-yl-2-phenylacetamides as Novel, Non-Urea-Containing GIRK1/2...
CAS 2126040-21-7
MW: 349.83 D
From 38.00€ *
Review