Description: Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of oxaprozin is as a Cyclooxygenase Inhibitor. The chemical classification of oxaprozin is Nonsteroidal Anti-inflammatory Compounds. Target: COX, NF-kappaB. Smiles: C(CC(O)=O)C1=NC(=C(O1)C2=CC=CC=C2)C3=CC=CC=C3....

Oxaprozin is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 2.2 and 36 µM for human COX-1 and COX-2, respectively). It decreases acetic acid-induced writhing times and carrageenan-induced paw edema in mice when administered at doses of 100 and 70 mg/kg, respectively. Formulations...