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Item number: Cay17131-10

Dabigatran etexilate is a prodrug form of the thrombin inhibitor dabigatran (Cay-17133). It inhibits thrombin-induced platelet aggregation in isolated rabbit platelets (IC50 = 0.337 µM) and inhibits thrombus formation in a rat model of venous thrombosis (ED50 = 7.8 µmol/kg). Formulations containing dabigatran...

Keywords:	BIBR 1048,...
Application:	Thrombin inhibitor prodrug
CAS	211915-06-9
MW:	627.7 D

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Dabigatran etexilate

Item number: TGM-T0389-2mg

Description: Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor that binds to thrombin, blocking its thrombogenic activity and preventing thrombus formation. Target: Thrombin. Smiles: CCCCCCOC(=O)N\N=C\c1ccc(NCc2nc3cc(ccc3n2C)C(=O)N(CCC(=O)OCC)c2ccccn2)cc1. References: Wienen W, et al. Thromb Haemost, 2007,...

Keywords:	BIBR 1048
CAS	211915-06-9
MW:	627.73 D

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