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Z-IETD-FMK
Z-IETD-FMK

Item number: Cay42519-1

A peptide inhibitor of caspase-8, inhibits TNF-alpha-induced apoptosis in isolated human neutrophils at 3 or 10 µM, decreases HRV replication and HRV-induced apoptosis in HeLa cells at 100 µM, reduces tumor growth and increases tumor macrophage and T cell infiltration in a mouse model of NMU-induced lung cancer when...
Keywords: Cbz-Ile-Glu(OMe)-Thr-Asp(OMe)-CH2F,...
Application: Caspase-8 inhibitor
CAS 210344-98-2
MW: 654.68 D
From 246.00€ *
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Z-IETD-FMK
Z-IETD-FMK

Item number: TGM-T7019-10mg

Description: Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a cell-permeable, selective inhibitor of caspase 8. Target: Caspase. Smiles: CC[C@H](C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)OC)C(=O)CF. References: Tezel G, et al. Invest Ophthalmol Vis Sci. 1999, 40(11), 2660-2667.
Keywords: Z-IE(OMe)TD(OMe)-FMK, Caspase-8 Inhibitor
CAS 210344-98-2
MW: 654.68 D
From 120.00€ *
Review