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Item number: Cay16439-5

Lysine-specific demethylase 1 (LSD1) belongs to the family of flavin adenine dinucleotide (FAD)-dependent amine oxidases that include monoamine oxidases (MAOs) and polyamine oxidase (PAO). LSD1 specifically demethylates mono- and dimethylated histone H3 lysine 4, resulting in transcriptional repression. It also...

Keywords:	rel-N-[(1R,2S)-2-phenylcyclopropyl]-4-piperidinamine, dihydrochloride
Application:	Irreversible LSD1 inhibitor
CAS	2102933-95-7
MW:	289.2 D

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GSK-LSD1 dihydrochloride

Item number: TGM-T2315-100mg

Description: GSK-LSD1 dihydrochloride (GSK-LSD1 2HCl) is a specificity irreversible LSD1 inhibitor (IC50: 16 nM). The selectivity of GSK-LSD1 for LSD1 is >1000 fold over other closely related FAD utilizing enzymes (i.e. MAO-A, LSD2, MAO-B). Target: Histone Demethylase. Smiles:...

Keywords:	GSK-LSD1 (hydrochloride), GSK-LSD1 2HCl
CAS	2102933-95-7
MW:	289.24 D

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