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Item number: Cay45336-10

GSK690 is a lysine-specific demethylase 1 (LSD1) inhibitor (IC50 = 0.09 µM in a cell-free assay). It is selective for LSD1 over monoamine oxidase A (MAO-A, IC50 = >200 µM). GSK690 inhibits LSD1 activity in THP-1 acute myeloid leukemia cells (IC50 = 1.4 µM). It potentiates reductions in viability of SJCRH30...

Keywords:	4-[2-(4-methylphenyl)-5-[(3R)-3-pyrrolidinylmethoxy]-3-pyridinyl]-benzonitrile
Application:	LSD1 inhibitor
CAS	2101305-84-2
MW:	369.47 D

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GSK-690

Item number: TGM-T27488-10mg

Description: GSK-690 is a selective and potent inhibitor of lysine demethylase 1 (LSD 1), which induces differentiation of leukemic stem cells in acute myeloid leukemia (AML), and can be used in the study of leukemias. Target: Histone Demethylase. Smiles:...

Keywords:	GSK 690, GSK690
CAS	2101305-84-2
MW:	369.46 D

From 276.00€ *

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