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DBZ
DBZ

Item number: Cay14627-5

gamma-Secretase is a multi-subunit aspartyl protease that cleaves amyloid precursor protein (APP) and many other type 1 transmembrane proteins, including Notch, E-cadherin, and ErbB4. The proteolysis of APP by secretases produces beta amyloid (Abeta), a 39- to 42-amino acid peptide which forms the amyloid plaques...
Keywords: YO-01027, Dibenzazepine,...
Application: gamma-secretase inhibitor
CAS 209984-56-5
MW: 463.5 D
From 49.00€ *
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Deshydroxy LY-411575
Deshydroxy LY-411575

Item number: LKT-D1773.25

gamma-Secretase inhibitor.
Keywords: YO-01027, Dibenzazepine
Application: gamma-Secretase inhibitor
CAS 209984-56-5
MW: 463.48 D
From 104.00€ *
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YO-01027
YO-01027

Item number: TGM-T6135-10mg

Description: YO-01027 (DBZ) is a potent gamma-secretase inhibitor. Target: Gamma-secretase. Smiles: C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@H]1c2ccccc2-c2ccccc2N(C)C1=O. References: Groth C, et al, Mol Pharmacol, 2010, 77(4), 567-574.
Keywords: gamma-Secretase Inhibitor XX , Dibenzazepine , DBZ
Application: gamma-secretase inhibitor
CAS 209984-56-5
MW: 463.48 D
From 30.00€ *
Review