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KDM4D-IN-1
Item number: TGM-T4214-100mg
Description: KDM4D-IN-1 is a KDM4D inhibitor (IC50: 0.41±0.03 µM). Target: Histone Demethylase. Smiles: Cc1nn2c(nc(O)c3cccnc23)c1C#N. References: Fang Z, et al. Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors. Bioorg Med Chem Lett....
| Application: | JMJD2D (KDM4) inhibitor |
| CAS | 2098902-68-0 |
| MW: | 225.21 D |
From 71.00€
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KDM4D-IN-1
Item number: Cay37431-1
KDM4D-IN-1 is an inhibitor of the histone demethylase jumonji domain-containing 2D (JMJD2D, IC50 = 0.41 µM). It is selective for JMJD2D over JMJD1B, JMJD2B, and jumonji AT rich interactive domain-containing protein 1A (JARID1A, IC50s = >10 µM for all). KDM4D-IN-1 (0.5 µM) decreases the colony formation, migration,...
| Keywords: | KDM4D Inhibitor 1, 4,5-dihydro-2-methyl-5-oxo-pyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile |
| Application: | JMJD2D (KDM4) inhibitor |
| CAS | 2098902-68-0 |
| MW: | 225.2 D |
From 90.00€
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