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Item number: Cay16365-5

alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...

Keywords:	Octyl-2-HG, 2-hydroxy-pentanedioic acid, 1-octyl ester
Application:	Cell-permeable 2-HG derivative
CAS	2097068-39-6
MW:	260.3 D

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