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MELK-8a (hydrochloride)
Item number: Cay37025-10
MELK-8a is an inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 0.002 µM). It is selective for MELK over FLT3, haspin, KIT, and PDGFRalpha, (IC50s = 0.18, 0.19, >10, and 0.42 µM, respectively), as well as a panel of 456 kinases at 1 µM. MELK-8a inhibits the proliferation of MDA-MB-468 and MCF-7...
| Keywords: | NVS-MELK8a, 1-methyl-4-[4-[4-[3-(4-piperidinylmethoxy)-4-pyridinyl]-1H-pyrazol-1-yl]phenyl]-piperazine, monohydrochloride |
| Application: | MELK inhibitor |
| CAS | 2096992-20-8 |
| MW: | 469 D |
From 134.00€
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MELK-8a hydrochloride
Item number: TGM-T11996-100mg
Description: MELK-8a hydrochloride is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK, IC50 = 2 nM). Target: MELK. Smiles: Cl.CN1CCN(CC1)c1ccc(cc1)-n1cc(cn1)-c1ccncc1OCC1CCNCC1. References: Touré BB, et al. Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery,...
| Application: | MELK inhibitor |
| CAS | 2096992-20-8 |
| MW: | 469.02 D |
From 37.00€
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