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Item number: Cay43638-1

A histamine H4 receptor antagonist (Ki = 6.17 nM), prevents histamine-induced shape change, CD11b protein upregulation, and actin polymerization in isolated human eosinophils (IC50s = 0.65, 4.9, and 1.3 nM, respectively), inhibits histamine-induced calcium influx in primary mouse dorsal root ganglion neurons at 10...

Keywords:	PF-3893787, ZPL-389, N4-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)-1-pyrrolidinyl]-2,4-pyrimidinediamine, dihydrochloride...
Application:	Histamine H4 receptor antagonist
CAS	2096455-90-0
MW:	335.3 D

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Adriforant hydrochloride

Item number: TGM-T12435-100mg

Description: Adriforant hydrochloride is an antagonist of histamine H4 receptor. Target: Others. Smiles: Cl.Cl.Cl.CN[C@@H]1CCN(C1)c1cc(NCC2CC2)nc(N)n1. References: Mowbray CE, et al. Challenges of drug discovery in novel target space. The discovery and evaluation of PF-3893787: a novel histamine H4 receptor...

Keywords:	PF-3893787 hydrochloride
CAS	2096455-90-0
MW:	371.74 D

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