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Item number: Cay44353-1

BI-907828 is an inhibitor of the protein-protein interaction between p53 and murine double minute 2 (MDM2, IC50 = 2 nM in a cell-free assay). It is selective for the p53-MDM2 interaction over the p53-MDMX interaction (IC50 = 7,944 nM). BI-907828 selectively inhibits the proliferation of Colon-26 colon cancer cells,...

Keywords:	Brigimadlin, (2'S,3'S,...
Application:	p53-MDM2 protein-protein interaction inhibitor
CAS	2095116-40-6
MW:	591,46 D

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Brigimadlin

Item number: TGM-T69923-25mg

Description: Brigimadlin (BI 907828) is an orally active and highly potent E3 ubiquitin-protein ligase MDM2-p53 antagonist with antitumor activity.Brigimadlin can be used to study metastatic BTC, PDAC, lung adenocarcinoma, or bladder cancer. Target: MDM-2/p53, E1/E2/E3 Enzyme, Mdm2, p53. Smiles:...

Keywords:	BI 907828 , BI907828 , BI-907828
Application:	Targets E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] (MDM2)
CAS	2095116-40-6
MW:	591.46 D

From 152.00€ *

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