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Item number: TGM-T17010-100mg

Description: TC13172 is an inhibitor of mixed lineage kinase domain-like protein (EC50: 2 nM for HT-29 cells). Target: Others. Smiles: Cn1c(nc2n(CC#Cc3cccc(O)c3)c(=O)n(C)c(=O)c12)S(C)(=O)=O

CAS	2093393-05-4
MW:	388.4 D

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TC 13172

Item number: Cay31034-1

An inhibitor of MLKL and necroptosis, selective for MLKL over RIPK1 and RIPK3 at 10 µM, inhibits TSZ-induced necroptosis in HT-29 cells (EC50 = 2 nM), inhibits TSZ-induced oligomerization of MLKL and translocation of MLKL to the plasma membrane in HT-29 cells at 100 nM. Formulation: A solid. InChI:...

Keywords:	3,7-dihydro-3-[3-(3-hydroxyphenyl)-2-propyn-1-yl]-1,7-dimethyl-8-(methylsulfonyl)-1H-purine-2,6-dione
Application:	MLKL / necroptosis inhibitor
CAS	2093393-05-4
MW:	388.4 D

From 76.00€ *

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