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LYN-1604
Item number: TGM-T4123-100mg
Description: LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis. Target: Apoptosis, Autophagy. Smiles: C(CN1CCN(C(CN(CC(C)C)CC(C)C)=O)CC1)(OCC2=CC3=C(C=C2)C=CC=C3)C4=C(Cl)C=C(Cl)C=C4. References: Zhang L, Fu L, Zhang S, Zhang J,...
| Keywords: | LYN1604 |
| Application: | ULK1 activator |
| CAS | 2088939-99-3 |
| MW: | 584.62 D |
From 105.00€
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LYN-1604
Item number: Cay24007-1
LYN-1604 is an activator of unc-51-like kinase 1 (ULK1, EC50 = 18.94 nM). It increases Beclin 1, LC3-II, and total LC3 protein levels and reduces levels of p62 in human MDA-MB-231 triple-negative breast cancer (TNBC) cells in a concentration-dependent manner, indicating an increase in autophagy. It also increases...
| Keywords: | 2-[bis(2-methylpropyl)amino]-1-[4-[2-(2,4-dichlorophenyl)-2-(2-naphthalenylmethoxy)ethyl]-1-piperazinyl]-ethanone |
| Application: | ULK1 activator |
| CAS | 2088939-99-3 |
| MW: | 584.6 D |
From 111.00€
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