3 products were found matching "208255-80-5"!
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DAPT
Item number: Cay13197-25
gamma-Secretase is a multi-subunit aspartyl protease that cleaves amyloid precursor protein (APP) and many other type 1 transmembrane proteins, including Notch, E-cadherin, and ErbB4. The proteolysis of APP by secretases produces beta amyloid (Abeta), a 39- to 42-amino acid peptide which forms the amyloid plaques...
| Keywords: | GSI-IX, N-[2S-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-glycine, 1,1-dimethylethyl ester |
| Application: | gamma-secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432.5 D |
From 77.00€
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DAPT
Item number: AG-CR1-0016-M005
Cell permeable gamma-secretase inhibitor (IC50 = 115 nM for total beta-amyloid, IC50 = 200 nM for beta-amyloid 1-42), Reduces Abeta levels in vivo, Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD), Does not inhibit persenilinase, Notch processing inhibitor, Enhances...
| Keywords: | N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester |
| Application: | gamma-secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432,5 D |
From 77.00€
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DAPT
Item number: LKT-D0260.1
gamma-Secretase inhibitor.
| Keywords: | GSI-IX |
| Application: | gamma-Secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432.47 D |
From 90.00€
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