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Item number: Cay41030-10

NEO2734 is a dual inhibitor of the bromodomain and extra terminal domain family of proteins (BET) and p300/CREB-binding protein (CBP). It binds to bromodomain-containing protein 2 (BRD2), BRD3, and BRD4 (Kds = 3.2, 2.3, and 6.5 nM, respectively), bromodomain testis-specific protein 1 (BRDT1) and BRDT2 (Kds = 3.1 and...

Keywords:	1,3-dimethyl-5-[2-(tetrahydro-2H-pyran-4-yl)-1-[2-(trifluoromethoxy)ethyl]-1H-benzimidazol-6-yl]-2(1H)-pyridinone
Application:	p300/CBP / BET bromodomains dual inhibitor
CAS	2081072-29-7
MW:	435.4 D

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NEO2734

Item number: TGM-T8658-100mg

Description: NEO2734 (EP31670) is an orally active, selective inhibitor of p300/CBP and BET bromodomains, with an IC50 of less than 30 nM for both targets. Target: Histone Acetyltransferase, Epigenetic Reader Domain. Smiles: Cc1cc(cn(C)c1=O)-c1ccc2nc(C3CCOCC3)n(CCOC(F)(F)F)c2c1. References: The novel BET-CBP/p300...

Keywords:	EP31670
Application:	p300/CBP / BET bromodomains dual inhibitor
CAS	2081072-29-7
MW:	435.44 D

From 109.00€ *

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