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Item number: Cay18319-1

Aldehyde dehydrogenases (ALDHs) catalyze the NAD(P)+-dependent oxidation of aldehyde-containing substrates to the corresponding carboxylic acids. ALDH1A1 activity is elevated in certain stem cells and cancers. NCT-501 is a potent, reversible, theophylline-based inhibitor of ALDH1A1 (IC50 = 40 nM for the human form)....

Keywords:	8-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)-1H-purine-2,6-dione,...
Application:	Reversible ALDH1A1 inhibitor
CAS	2080306-22-3
MW:	453 D

From 89.00€ *

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NCT-501 hydrochloride

Item number: TGM-T39485-10mg

Description: NCT-501 hydrochloride is a highly potent and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), which is based on theophylline. It effectively inhibits hALDH1A1 with an IC50 value of 40 nM, exhibiting superior selectivity towards hALDH1A1 compared to other ALDH isozymes and dehydrogenases such...

Application:	Reversible ALDH1A1 inhibitor
CAS	2080306-22-3
MW:	452.98 D

From 187.00€ *

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