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TP-472
Item number: TGM-T13190-1mg
Description: TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM). Target: Epigenetic Reader Domain. Smiles: CC(=O)c1cc(-c2cc(ccc2C)C(=O)NC2CC2)c2ncccn12. References: Moustakim M, et al. Chemical probes and inhibitors of bromodomains outside the BET family. Medchemcomm. 2016 Dec 7,7(12):2246-2264.
| Application: | BRD9/7 probe |
| CAS | 2079895-62-6 |
| MW: | 333.38 D |
From 106.00€
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TP-472
Item number: Cay20030-1
TP-472 is an inhibitor of bromodomain BRD9 (Kd = 33 nM, EC50 = 320 nM in a NanoBRET assay). It has >30-fold selectivity over all other bromodomain family members with the exception of the highly homologous BRD7 bromodomain (Kd = 340 nM in an isothermal titration calorimetry (ITC) assay). See the Structural Genomic...
| Keywords: | 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl-benzamide |
| Application: | BRD9/7 probe |
| CAS | 2079895-62-6 |
| MW: | 333.4 D |
From 44.00€
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