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TP-472
TP-472

Item number: Cay20030-1

TP-472 is an inhibitor of bromodomain BRD9 (Kd = 33 nM, EC50 = 320 nM in a NanoBRET assay). It has >30-fold selectivity over all other bromodomain family members with the exception of the highly homologous BRD7 bromodomain (Kd = 340 nM in an isothermal titration calorimetry (ITC) assay). See the Structural Genomic...
Keywords: 3-(6-acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methyl-benzamide
Application: BRD9/7 probe
CAS 2079895-62-6
MW: 333.4 D
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