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Item number: Cay41101-1

BAY-2433334 is an inhibitor of Factor XIa (IC50 = 0.92 nM). It is greater than 1,000-fold selective for Factor Xa over FVIIa, FIXa, FXa, thrombin, urokinase, tissue plasminogen activator, and plasmin. BAY-2433334 increases clotting time in isolated human plasma (EC150 = 0.2 µM). In vivo, BAY-2433334 (10 and 30...

Keywords:	Asundexian,...
Application:	Factor XIa inhibitor
CAS	2064121-65-7
MW:	592.9 D

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Asundexian

Item number: TGM-T39463-1mg

Description: Asundexian (BAY-2433334) is a potent and orally active inhibitor of the coagulation factor FXIa that directly and reversibly binds to the active site of FXIa, thereby inhibiting its activity.Asundexian has an IC50 of 1 nM for human FXIa in buffer.Asundexian has antitumor activity and may be useful in...

Keywords:	Asundexian, BAY 2433334, BAY2433334, BAY-2433334
Application:	Targets coagulation factor XI [EC:3.4.21.27] (F11)
CAS	2064121-65-7
MW:	592.93 D

From 178.00€ *

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