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Item number: Cay15866-10

Darunavir is an HIV-1 protease inhibitor. It is active against HIV-1LAI in MT-2 cells (IC50 = 3 nM) with a cytotoxic concentration (CC50) of 74.4 µM. Darunavir is also active against wild-type and multidrug-resistant clinical isolates of HIV-1 in phytohemagglutinin-activated peripheral blood mononuclear cells...

Keywords:	TMC114, N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-carbamic acid,...
Application:	HIV-1 protease inhibitor
CAS	206361-99-1
MW:	547.7 D

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Darunavir

Item number: TGM-T2324-100mg

Description: Darunavir (TMC114) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS. Due to the emergence of ANTIVIRAL DRUG RESISTANCE when used alone, it is administered in combination with other ANTI-HIV AGENTS. Target: HIV Protease. Smiles:...

Keywords:	TMC114
Application:	Targets HIV protease [EC:3.4.23.16 3.4.23.47] (PR)
CAS	206361-99-1
MW:	547.66 D

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