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WM-1119
Item number: TGM-T4679-100mg
Description: WM-1119 is a highly potent, selective KAT6A/B inhibitor. Target: Histone Acetyltransferase. Smiles: Fc1cc(cc(c1)-c1ccccn1)C(=O)NNS(=O)(=O)c1ccccc1F. References: Baell JB et al. Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth. Nature. 2018 Aug,560(7717):253-257.
| Keywords: | WM1119 |
| Application: | KAT6A inhibitor |
| CAS | 2055397-28-7 |
| MW: | 389.38 D |
From 46.00€
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WM-1119
Item number: Cay30509-5
WM-1119 is an orally bioavailable inhibitor of lysine acetyltransferase 6A (KAT6A/MOZ, IC50 = 6.3 nM). It binds to KAT6A with a Kd value of 2 nM and is selective for KAT6A over KAT5 and KAT7 (Kds = 2,200 and 500 nM, respectively), as well as over a panel of 159 additional targets at 1 and 10 µM. WM-1119 inhibits...
| Keywords: | 3-fluoro-5-(2-pyridinyl)-benzoic acid, 2-[(2-fluorophenyl)sulfonyl]hydrazide |
| Application: | KAT6A inhibitor |
| CAS | 2055397-28-7 |
| MW: | 389.4 D |
From 150.00€
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