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Item number: Cay45304-1

A dual PARP1/2 and TNKS1/2 inhibitor, reduces the proliferation of Capan-1 PDAC cells (IC50 = 0.1895 µM), selectively inhibits the proliferation of, and induces apoptosis and G2/M phase cell cycle arrest in, HPAF-II and AsPC-1 PDAC cells expressing RNF43 loss-of-function mutations over SNU-410 PDAC cells expressing...

Keywords:	JPI-547, 6-[4-[(1,2,3,4,5,6-hexahydro-5-oxobenzo[h]-1,6-naphthyridin-8-yl)methyl]-1-piperazinyl]-3-pyridinecarbonitrile
Application:	Dual PARP1/2 / TNKS1/2 inhibitor
CAS	2055357-64-5
MW:	400.49 D

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Nesuparib

Item number: TGM-T61932-100mg

Description: Nesuparib (JPI-547/OCN-201) is a potent PARP inhibitor with inhibitory effects on PARP and TNKS1.Nesuparib has antitumor activity and can be used in the treatment of tumors, endocrine and metabolic disorders, genitourinary disorders, and can be used in the study of neuropathic pain, neurodegenerative...

Keywords:	JPI-547/OCN-201
CAS	2055357-64-5
MW:	400.48 D

From 85.00€ *

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