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Item number: Cay31066-1

SR 12460 is a mimetic of the IkappaB kinase beta (IKKbeta) NEMO/IKKgamma-binding domain (NBD) that inhibits the protein-protein interaction between the IKK complex subunits NF-kappaB essential modulator (NEMO/IKKgamma) and IKKbeta. It inhibits TNF-alpha-induced NF-kappaB activation in a reporter assay when used at...

Keywords:	N-(5-chloro-2-pyridinyl)-2-[[2-(3,5-difluorophenyl)ethyl]amino]-acetamide
Application:	IKKbeta NBD mimetic
CAS	2055101-66-9
MW:	325.7 D

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