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Item number: TGM-T16449-10mg

Description: PD176252 is a potent BB1 and BB2 antagonist with inhibitory effects on BB1 and BB2 receptors.PD176252 acts as a small molecule GRPR inhibitor and FPR1/FPR2 agonist to inhibit the growth and proliferation of a variety of cancer cells. Target: Bombesin Receptor. Smiles:...

CAS	204067-01-6
MW:	584.67 D

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PD 176252

Item number: Cay42037-1

A nonpeptide antagonist of BB1 and BB2 (Kis = 0.17 and 1 nM, respectively), induces calcium mobilization in HL-60 cells expressing FPR1 or FPR2/ALX (EC50s = 0.31 and 0.66 µM, respectively), inhibits the proliferation of C6 glioma cells (IC50 = 2 µM), increases social interaction in the social interaction test in...

Keywords:	(aS)-N-[[1-(5-methoxy-2-pyridinyl)cyclohexyl]methyl]-a-methyl-a-[[[(4-nitrophenyl)amino]carbonyl]amino]-1H-indole-3-propan...
Application:	Neuromedin B receptor (BB1) / gastrin-releasing peptide receptor (BB2) nonpeptide antagonist
CAS	204067-01-6
MW:	584.7 D

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