2 products were found matching "2035509-96-5"!
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AX-15836
Item number: Cay28774-1
An ERK5 inhibitor (IC50 = 8 nM), selective for ERK5 over a panel of 100 other kinases at 1 µM, inhibits ERK5 autophosphorylation in HeLa cells at 1 µM, induces apoptosis in combination with ivermectin in A375 spheroids at 1 µM, decreases skin thickness and scaling in a mouse model of imiquimod-induced allergic skin...
| Keywords: | 2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dihydro-5-methyl-11-(methylsulfonyl)... |
| Application: | ERK5 inhibitor |
| CAS | 2035509-96-5 |
| MW: | 648.78 D |
From 58.00€
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AX-15836
Item number: TGM-T14360-100mg
Description: AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM). Target: ERK. Smiles: CCOc1cc(ccc1Nc1ncc2N(C)C(=O)c3ccccc3N(c2n1)S(C)(=O)=O)C(=O)N1CCC(CC1)N1CCN(C)CC1. References: Lin EC, et al. ERK5 kinase activity is dispensable for cellular immune response and proliferation. Proc Natl Acad Sci U S A. 2016 Oct...
| CAS | 2035509-96-5 |
| MW: | 648.78 D |
From 49.00€
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