Solamargine is a glycoalkaloid that has been found in S. lycocarpum and has anticancer activity. It decreases viability of H1650, H1975, PC-9, A549, and H1299 non-small cell lung cancer (NSCLC) cells when used at a concentration of 6 µM. Solamargine increases ERK1/2 phosphorylation and decreases the expression of...

Description: Solamargine (delta-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL), has been shown to inhibit growth and induce apoptosis of various cancer cells. Target: Apoptosis, p38 MAPK, P-gp, STAT. Smiles:...