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Safinamide (mesylate)
Item number: Cay21546-50
Safinamide is an inhibitor of monoamine oxidase B (MAO-B, IC50 = ~0.1 µM). It is selective for MAO-B over MAO-A (IC50 = >10 µM). It also inhibits radioligand binding to sodium channel binding site 2, sigma-1, and sigma-2 receptors in rat brain membranes (IC50s = 8.2, 0.019, and 1.59 µM, respectively). Safinamide...
| Keywords: | EMD 1195686, FCE 26743, NW-1015, PNU-151774E, 2S-[[[4-[(3-fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide,... |
| Application: | Reversible MAO-B inhibitor |
| CAS | 202825-46-5 |
| MW: | 398.4 D |
From 97.00€
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Safinamide mesylate
Item number: TGM-T6651-100mg
Description: Safinamide mesylate (EMD 1195686 mesylate) , a mesylate salt of Safinamide, can reversibly and specifically inhibit MAO-B (IC50: 98 nM), has 5918-fold selectivity against MAO-A. Target: Monoamine Oxidase, MAO. Smiles: CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2cccc(F)c2)cc1)C(N)=O. References: Binda C, et al. J...
| Keywords: | EMD 1195686 mesylate , FCE28073 mesylate |
| Application: | Targets monoamine oxidase [EC:1.4.3.4] (MAO, aofH) |
| CAS | 202825-46-5 |
| MW: | 398.45 D |
From 30.00€
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