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Item number: Cay45828-10

Apilimod is an inhibitor of the class III phosphatidylinositol kinase PIKfyve (IC50 = 14 nM). It is selective for PIKfyve over 10 other lipid kinases and 31 other protein kinases (IC50s = >9.1 µM for all). Apilimod inhibits the production of IL-12p40 induced by IFN-gamma and LPS or the TLR7 agonist R-837 (imiquimod,...

Keywords:	STA-5326, (E)-4-(6-(2-(3-methylbenzylidene)hydrazineyl)-2-(2-(pyridin-2-yl)ethoxy)pyrimidin-4-yl)morpholine, methanesulfonate
Application:	PIKfyve inhibitor
CAS	2026610-35-3
MW:	418.5 D

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