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Item number: ABD-13401

A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.

Application:	Caspase-3 substrate
CAS	201608-14-2

139.00€ *

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Ac-DEVD-AFC

Item number: Cay14459-1

During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 µM), as well as related caspases. Caspase activity can be quantified by...

Keywords:	Caspase-3 Substrate (Fluorogenic), N-Acetyl-Asp-Glu-Val-Asp-7-amino-4-Trifluoromethylcoumarin,...
Application:	Caspase activity studies
CAS	201608-14-2
MW:	729.6 D

From 68.00€ *

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