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CHS-828
Item number: TGM-T1998-100mg
Description: CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM). Target: Apoptosis, NAMPT. Smiles: Clc1ccc(OCCCCCCNC(NC#N)=Nc2ccncc2)cc1. References: Watson M, et al. Mol Cell Biol. 2009, 29(21), 5872-5888.
| Keywords: | CHS 828, GMX1778 |
| CAS | 200484-11-3 |
| MW: | 371.86 D |
From 31.00€
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CHS-828
Item number: AG-CR1-0064-M005
Antitumor compound, Programmed cell death inducer, Cytotoxic, Antiproliferative, p53 activator, IkappaB kinase inhibitor, NF-kappaB inhibitor, Nampt/visfatin inhibitor.
| Keywords: | GMX1778, (E)-1-[6-(4-chlorophenoxy)hexyl]-2-cyano-3-(pyridin-4-yl)guanidine |
| Application: | Apoptosis inducer |
| CAS | 200484-11-3 |
| MW: | 371,9 D |
From 77.00€
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CHS-828
Item number: Cay11021-10
CHS-828 is a nicotinamide phosphoribosyltransferase (Nampt) inhibitor (IC50 = + levels in, and is cytotoxic to, HeLa cervical cancer cells. It decreases ATP levels in C666-1 nasopharyngeal and FaDu head and neck squamous cell carcinoma (HNSCC) cells in a time-dependent manner when used at concentrations of 10 and 20...
| Keywords: | GMX 1778, N-[6-(4-chlorophenoxy)hexyl]-N'-cyano-N''-4-pyridinyl-guanidine |
| Application: | Apoptosis inducer |
| CAS | 200484-11-3 |
| MW: | 371.9 D |
From 100.00€
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