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Item number: TGM-TQ0050-100mg

Description: NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM). Target: Histone Demethylase. Smiles: Oc1cc(cc2cccnc12)-c1cccc(c1)C(=O)NCCCc1ccccc1. References: Duan L, et al. KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and...

Keywords:	KDM4B Inhibitor B3
Application:	KDM4B/JMJD2B histone lysine demethylase inhibitor
CAS	2003260-55-5
MW:	382.45 D

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NCGC00244536

Item number: Cay18478-1

NCGC00244536 is an inhibitor of KDM4B/JMJD2B histone lysine demethylase (IC50 = ~10 nM). It is selective for KDM4B/JMJD2B over KDM5A/JARID1 and lysine-specific demethylase 1 (LSD1) but does inhibit KDM4A/JMJD2A, KDM4C/JMJD2C, and KDM4D/JMJD2D at 10 µM. NCGC00244536 inhibits the growth of PC3, DU145, LNCaP, VCaP, and...

Keywords:	3-(8-hydroxy-6-quinolinyl)-N-(3-phenylpropyl)-benzamide
Application:	KDM4B/JMJD2B histone lysine demethylase inhibitor
CAS	2003260-55-5
MW:	382.5 D

From 67.00€ *

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