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Item number: Cay23362-1

CGP 3466 is a GAPDH ligand. Immobilized CGP 3466 binds to GAPDH from rat hippocampus extracts and to purified recombinant rabbit muscle GAPDH using affinity purification. CGP 3466 reduces PAJU cell apoptosis induced by rotenone (Cay-13995). CGP 3466 dose-dependently increases survival of trophically withdrawn PC12...

Keywords:	CGP 3466B, N-methyl-N-2-propyn-1-yl-dibenz[b,f]oxepin-10-methanamine, (2Z)-2-butenedioate
Application:	GAPDH ligand
CAS	200189-97-5
MW:	391.4 D

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CGP 3466B maleate

Item number: TGM-T21792-1mL

Description: CGP 3466B maleate (Omigapil maleate) is an orally bioavailable GAPDH nitrosylation inhibitor. Omigapil maleate abrogates Abeta1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. Omigapil maleate has the potential for the research of Alzheimer's disease. Omigapil maleate...

Keywords:	Omigapil maleate, Omigapil (Maleate)
CAS	200189-97-5
MW:	391.42 D

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