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Item number: Cay22481-5

ML-329 is an inhibitor of the microphthalmia-associated transcription factor (MITF) pathway with an IC50 value of 1.2 µM for promoter activity of the MITF target gene TRPM-1. It is selectively cytotoxic to the SK-MEL-5 and MALME-3M MITF-dependent melanoma cell lines over A375 MITF-independent cells (IC50s = 0.1,...

Keywords:	4-[(1,4-dihydro-1,4-dioxo-2-naphthalenyl)amino]-benzenesulfonamide
Application:	MITF inhibitor
CAS	19992-50-8
MW:	328.3 D

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