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Ro 61-8048
Item number: TGM-T1896-100mg
Description: Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM. Target: Hydroxylase. Smiles: COc1ccc(cc1OC)S(=O)(=O)Nc1nc(cs1)-c1cccc(c1)[N+]([O-])=O. References: Röver S, et al. J Med Chem. 1997, 40(26), 4378-4385.
| Application: | Kynurenine 3-hydroxylase inhibitor |
| CAS | 199666-03-0 |
| MW: | 421.45 D |
From 34.00€
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Ro 61-8048
Item number: Cay15199-5
The kynurenine pathway mediates the metabolism of L-tryptophan to NAD+ and is particularly important in neurophysiology. Ro 61-8048 is a potent inhibitor of kynurenine 3-hydroxylase (IC50 = 37 nM), preventing the conversion of kynurenine (Cay-11305) to 3-hydroxy kynurenine. Ro 61-8048 inhibition of kynurenine...
| Keywords: | 3,4-dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]-benzenesulfonamide |
| Application: | Kynurenine 3-hydroxylase inhibitor |
| CAS | 199666-03-0 |
| MW: | 421.4 D |
From 111.00€
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Ro 61-8048
Item number: LKT-R5700.25
Kynurenine 3-hydroxylase inhibitor.
| Application: | Kynurenine 3-hydroxylase inhibitor |
| CAS | 199666-03-0 |
| MW: | 421.44 D |
From 175.00€
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