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FEN1-IN-4
FEN1-IN-4

Item number: TGM-T8545-100mg

Description: FEN1-IN-4 (FEN1 Inhibitor C2) is an inhibitor of human flap endonuclease-1 (hFEN1). Target: Others. Smiles: On1c(=O)n(CC2CC2)c2ccccc2c1=O. References: Jack C Exell, et al. Cellularly Active N-hydroxyurea FEN1 Inhibitors Block Substrate Entry to the Active Site. Nat Chem Biol. 2016 Oct,12(10):815-21.
Keywords: FEN1 Inhibitor C2
Application: FEN1 inhibitor
CAS 1995893-58-7
MW: 232.24 D
From 42.00€ *
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FEN1-IN-4
FEN1-IN-4

Item number: Cay37790-1

FEN1-IN-4 is an inhibitor of flap endonuclease 1 (FEN1, IC50 = 30 nM for FEN1-336Delta). It also inhibits exonuclease 1 in a concentration-dependent manner. FEN1-IN-4 (10 µM) inhibits ATP-induced mitochondrial DNA (mtDNA) fragmentation and levels of cytosolic mtDNA in LPS-primed primary mouse bone marrow-derived...
Keywords: FEN1 Inhibitor 4, Flap Endonuclease 1 Inhibitor 4, 1-(cyclopropylmethyl)-3-hydroxy-2,4(1H,3H)-quinazolinedione
Application: FEN1 inhibitor
CAS 1995893-58-7
MW: 232.2 D
From 49.00€ *
Review