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Item number: Cay35108-1

Y-33075 is an inhibitor of Rho-associated kinase 2 (ROCK2, IC50 = 3.6 nM). It is selective for ROCK2 over PKC and calcium/calmodulin-dependent protein kinase II (CaMKII, IC50s = 420 and 810 nM, respectively). Topical application of Y-33075 (0.05% v/v) reduces intraocular pressure in rabbit and cynomolgus monkeys....

Keywords:	RKI-983, SNJ-1656, Y-39983, 4-[(1R)-1-aminoethyl]-N-1H-pyrrolo[2,3-b]pyridin-4-yl-benzamide
Application:	ROCK2 inhibitor
CAS	199433-58-4
MW:	280.3 D

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